Matthew Mifsud, MD

Surgical Oncology
Matthew Mifsud image
4.8 out of 5 
New patient visits

USF Health Department of Otolaryngology - Head and Neck Surgery

2 Tampa General Circle,
Tampa, FL 33606
Fax
813-821-9702
As a head and neck surgical oncologist, my major focus is the treatment within the head and neck region, affecting the face, neck, mouth and throat. At USF, I help lead a multidisciplinary team of medical professionals, that develop individualized cancer treatment plans, for each of our patients.





I have extensive surgical training and experience, which includes advanced subspecialization within my field of otolaryngology. This allows me to perform a wide array of surgical procedures and particularly focus on reconstructive surgery. This entails taking body parts from one area and transplanting them into the head and neck. This helps maintain a more normal physical appearance and optimizes speech/swallowing function, which can be impacted by cancer or other maladies. I'm able to not only treat a person's disease, but also help to optimize their quality of life long after treatment is complete.





In addition to cancer, I also focus on other complex head and neck conditions, such as those affecting the salivary glands, thyroid, and trachea. At USF, I also engage in various teaching and research activities, which enhance my ability to provide state-of-the-art care to all my patients.


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Verified Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
4.8 out of 5
367 ratings,
44 reviews
12/31/2025
I was blown away by Dr. Mifsud's positive attitude and energy. He explained things so very well!
12/12/2025
Couldn't be better
12/10/2025
Excellent service
12/10/2025
I was in/out in less than 30 minutes. Terrific!
12/10/2025
I'M IN GOOD HANDS.

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Map & Directions

USF Health Department of Otolaryngology - Head and Neck Surgery

2 Tampa General CircleTampa, FL 33606
Monday - Friday

8:00 am - 5:00 pm

Saturday - Sunday

Closed

Fax